
What is Epigenetics?
How It Works and Affects Your Skin
What is
Epigenetics?
Understanding Epigenetics helps show why it’s so important for you to take care of your skin with good habits and the right skincare products.
The role of epigenetic factors in
Skin Ageing
Epigenetics shows that skin ageing is not solely determined by your DNA, it’s also shaped by your daily habits. By making mindful choices to protect and nourish your skin, you can help slow the ageing process and promote long-term skin health.
How epigenetics
Affects the Skin

- UV exposure and skin ageing:
It’s well known that UV rays can induce oxidative stress, inflammatory reactions, DNA damage and reduce immune responses. However, they can also trigger epigenetic changes. All these effects can accelerate skin ageing, leading to the appearance of wrinkles and brown spots, for example. Sun protection can help protect your skin from these changes and contribute to slowing down the process of premature skin ageing induced by UV rays.
- Pollution and inflammation:
Pollution can cause inflammation and oxidative stress, which could lead to epigenetic changes resulting in increased collagen degradation. Regular cleansing and an intake of antioxidants could help protect your skin from some of these effects.
- Diet and skin health:
Foods rich in antioxidants help to protect your skin from oxidative stress, while a poor diet can trigger inflammation and skin lesions. Oxidative stress and inflammation may promote epigenetic changes and skin ageing. A balanced diet can help you maintain healthy-looking skin.
- Stress and skin sensitivity:
Chronic stress could activate certain genes that cause inflammation, which could lead to breakouts and dryness. Managing stress helps keep your skin calm and balanced.
- Sleep and skin regeneration:
Insufficient sleep disrupts your skin’s natural repair processes, while 7–9 hours of quality sleep can help support cell regeneration and healing. Getting enough rest is essential for maintaining healthy-looking skin.
- Exercise and collagen production:
Exercise boosts blood flow and activates genes that promote collagen production, helping your skin stay firm and elastic. As a result, regular exercise can support youthful-looking skin.
How to support healthy skin
Taking Epigenetics into Account?
Epigenetics
What is epigenetics: Epigenetics involves changes in gene activity that don’t alter the DNA sequence but affect how genes function, influencing traits like skin ageing.
Epigenetic factors: These are external and internal influences, like UV exposure, diet and stress, that affect gene activity and impact skin ageing and repair.
Can epigenetics be changed: Yes, lifestyle choices such as diet, sleep and stress management can influence gene expression and could therefore help slow down skin ageing and promote healthy skin.
How to support healthy skin through epigenetics: Adopting healthy habits, including eating antioxidant-rich foods, getting enough sleep and using protective skin care products could have a positive impact on gene expression and your skin’s appearance.
NIVEA
Skin Care Routine:
Start with a gentle, non-stripping cleanser to remove dirt, oil and pollutants from the surface of your skin. Pollution and environmental toxins can trigger oxidative stress and inflammation, which could have a negative epigenetic effect on your skin, leading to premature ageing. Neglecting the cleansing stage could also encourage the appearance of imperfections. A good cleanser clears these impurities without disrupting the skin’s natural moisture barrier, ensuring that your skin is clean and ready to absorb the next steps in your routine.
Discover NIVEA’s range of cleansers, designed to suit all skin types. From gentle micellar waters to pore-refining cleansers, NIVEA offers a variety of products to cleanse and refresh your skin.
After cleansing, use a toner to help restore your skin’s pH balance and ensure any remaining impurities are removed. Toners help refresh your skin and prepare it for the next steps in your skincare routine. Some toners contain ingredients like witch hazel, aloe vera or rose water, which have soothing properties.
Explore the NIVEA range of toners, formulated to balance and refresh your skin. Whether you’re looking to tighten pores, hydrate or revitalise, NIVEA offers a variety of toners to complement your skincare routine, leaving your skin feeling fresh and rejuvenated.

A high-performance serum is essential for targeting deeper skin concerns and enhancing renewal at a cellular level. The NIVEA Cellular Epigenetics Age Rewind Serum is expertly formulated with Epicellin, a revolutionary ingredient inspired by epigenetics, to help reactivate the youthful functions of skin cells. It also contains three types of hyaluronic acid to help lock in moisture and smooth out wrinkles. Designed to target the signs of ageing, this advanced formula acts on 10 visible signs of ageing, such as wrinkle volume, firmness and elasticity, for smoother, younger-looking, more radiant skin.
"There are different sizes of molecular hyaluronic acid which penetrate and add moisture to the skin at different levels, contributing to hydration, plumpness and wrinkle filling."
Dr Christiane Meyer, Head of R&D Face Category, Beiersdorf
Dr Cassandra Falckenhayn, Sr. Scientist Bioinformatics, Beiersdorf
Applying a moisturising cream helps to lock in moisture and maintain your skin barrier, helping to protect your skin from dehydration and environmental irritants.
Day creams help to lock in hydration, helping your skin to feel supple and supported throughout the day. The NIVEA Cellular Expert Filler Intensive Anti-Age Day Cream SPF 15 combines micro & macro hyaluronic acid and pure folic acid to fill wrinkles, smooth skin and enhance hydration. It works to help restore firmness and volume, giving your skin a plumper, more youthful look. Integrated SPF 15 combined with anti-UVA protection helps protect against UVA/UVB rays, helping to prevent premature skin ageing and UV-induced damage, while preserving your skin’s plumpness.
In the evening, swap to a night cream to intensely nourish your skin whilst you sleep. The NIVEA Cellular Expert Filler Intensive Anti-Age Night Care is designed to firm skin and reduce the signs of ageing while you sleep. Its formula combines ingredients such as hyaluronic acid and folic acid to support your skin’s natural cell renewal process overnight for a fresh, rested complexion when you wake up.
Explore the NIVEA range of sunscreens, designed to protect your skin from UV rays while keeping it hydrated. With options for all skin types, NIVEA sunscreens provide long-lasting protection, helping you maintain healthy-looking, comfortable skin in the sun.
A youthful appearance with the
NIVEA Cellular Expert Filler Range

Formulated with carefully selected active ingredients—such as pure folic acid, micro & macro hyaluronic acid, bakuchiol and Epicelline—different products in the range feature unique combinations tailored to target specific signs of ageing and promote a rejuvenated appearance.
"From a personal perspective, I love using the NIVEA Epigenetics Rejuvenating Serum, the texture and feel on my skin is great and I find my skin looks more youthful with continued use. Please do give it a go!"
Dr Angela Tewari, Consultant Dermatologist MBBS BSc MRCP(UK) PhD(London)











